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Courses

For the 20th MDDS, lectures will be held both online and in-presence.

Program

The lessons will be done in 2 different section:

  • I section focused on the topics of the medicinal chemistry
  • II section focused on the industry world

The courses will be followed by a ten-day drug development summer school. More information will be available soon.

Tutor

The tutors of the University Master’s program are the Professors:

  • Maurizio Taddei (UNISI)
  • Elena Petricci (UNISI)
  • Jean-Denis Docquier (UNISI)
  • Nicola Dimitri (UNISI)

Lectures

A.Y. 2025/26

Prof. Thierry Langer (University of Wien):

  • 1st part: Chemistry Driven Drug Discovery and Pharmacophores
  • 2nd part: Hit Identification by using Virtual Screening

Dr. Anna Visibelli (University of Siena): Introduction to Artificial Intelligence: Examples and Applications in Bioinformatics

Dr. Paolo Governa (University of Parma): Essential of Computer-Aided Drug Design: focus on ligandability and molecular similarity

Dr. Diego Fiorucci and Dr. Iuni Trist (Evotec): Polyhedric support to Drug Design

Dr. Andrea Sodini (University of Florence): Stereoselective O- and C-Glycosylation Reactions

Dr. Francesco Milanesi (University of Florence): Synthetic receptors for molecular recognition of carbohydrates: a pragmatic user’s guide

Dr. Lorena Tedeschi (CNR): Bioconjugation techniques for molecular and cellular imaging

Dr. Veronica Ghini (CERM): Metabolomics and drug discovery: general principles and applications in (metallo-) drug research

Dr. Luca Menichetti (CNR): Molecula imaging for drug design

Dr. Filippo Campana (University of Perugia): Green methodologies for the synthesis of pharmaceutically active compounds

Dr. Giulia Brufani (University of Perugia): Green methodologies for the synthesis of pharmaceutically active compounds. Laboratory of E-factor calculation

Prof. Jean-Denis Docquier (University of Siena): Innovation in the discovery and development of antibacterial drugs in the age of antibiotic resistance

Prof. Daniele Castagnolo (University College London):

  • 1st part: Sustainability in Medicinal Chemistry and Drug Synthesis
  • 2nd part: Introduction to biocatalysis

Dr. Fabio Rancati (Chiesi): Approaches to the development of chemical probes and inhaled drugs

Dr. Mirjam Cugini (MJ Consulting): Tools for Effective Personal and Interpersonal Communication

Dr. Claudia Sala (Fondazione Biotecnopolo di Siena): Drug discovery against tuberculosis

Dr. Simone Mantegazza (Dipharma Francis): From Route Design to Scale-Up: R&D Challenges in API Synthesis

Dr. Chiara Vladiskovic (Dipharma Francis): Polymorphism and solid state: a different challenge for the pharmaceutical industry

Dr. Federica Poggialini (University of Siena): Drug Like Properties in Drug Discovery

Dr. Giuseppina Truglio (University of Siena): Antibody-Drug Conjugates as Targeted Drug Delivery Systems: Beyond Conventional Cytotoxic Payloads

Prof. Marco Lolli and Prof. Stefano Sainas (University of Turin):

  • 1st part: The hit to lead process: focus on bioisosterism
  • 2nd part: Case history: discovery of human dihydroorotate dehydrogenase (hDHODH) inhibitors using a bioisosteric approach
  • 3rd part: Case history: preclinical development of human dihydroorotate dehydrogenase (hDHODH) inhibitors: how (try to) reach the Market

Prof. Walter Cabri (University of Bologna): Greening peptide synthesis

Dr. Giuseppe Giannini: Controlling oral microbiota/periodontitis – oral drugs and their impact on intestinal microbiota

Prof. Daria Bottai (University of Pisa): Antibody-Antibiotic Cojugates to fight bacterial infections: challenges and therapeutic potential

Dr. Francesca Ricci (Fondazione Mario Negri): Preclinical studies in the drug discovery and development processes

Dr. Carla Ferreri (CNR): Free radicals: from chemistry to biology ….generating sciencepreneurship

Prof. Nicola Dimitri (University of Siena): The economics of pharmaceutical research and development